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Table 3 Studies included in the review

From: Elevated preoperative CEA is associated with subclinical nodal involvement and worse survival in stage I non-small cell lung cancer: a systematic review and meta-analysis

  Low CEA High CEA
NO Author Year of publication No. of patients CEA cut-off No. of LN 5 year survival Recurrence No. of LN 5 year survival Recurrence
1 Ryo Maeda [29] 2017 378 5 ng/mL 263 N0, 15 N1–3 87.70%   81 N0, 19 N1–3 75.50%  
2 Yusuke Takahashi [30] 2015 171 5 ng/mL       
3 Gianfranco Buccheri [18] 2003 118 10 ng/mL    16%    70%
4 Riken Kawachi [31] 2009 815 5 ng/mL   76.70%    56.60%  
5 Niels Reinmuth [19] 2002 67 5 ng/mL       
6 Sukki Cho [32] 2013 770 3.5 ng/mL (mean)       
7 Kaoru Kaseda [33] 2016 246 5 ng/mL 168 N0, 19 N1-N2    47 N0, 12 N1-N2   
8 Tatsuya Kato [34] 2013 177 3 ng/mL   93.2% (ADC), 81% (SCC) 6.80%   59.4% (ADC), 51.9% (SCC) 38.80%
9 Terumoto Koike [35] 2012 894 5 ng/mL       
10 Hiroaki Komatsu [36] 2013 279 2.8 ng/mL 87 N0, 1 skip N2    143 N0, 11 skip N2   
11 Yasuhiro Tsutani [37] 2014 100 2.5 ng/mL       
12 Bo Ye [38] 2014 651 5 ng/mL 371 N0, 11 N1, 8 N2    211 N0, 32 N1,18 N2   
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Journal of Cardiothoracic Surgery

ISSN: 1749-8090

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